Local mixing time
Time for a sampled reactor region to remain within ±5% of its final tracer concentration.
Local mixing time [s]
BIOPROCESS ENGINEERING / COMPUTATIONAL FLUID DYNAMICS
One reactor.
Different exposures.
In a stirred bioreactor, average flow conditions can hide poor mixing, uneven dosing and wide differences in mechanical exposure. Explore the engineering indicators alongside original CFD visualizations.
OpenFOAM-based CFDMixing timeConcentration uniformityShear & dosing
01 / MIXING & PARTICLE STATISTICS
From mixing to exposure.
Compare distributions of mixing time, concentration uniformity, circulation and shear exposure. Select a bar to inspect the corresponding group.
Concentration uniformity
Distribution of normalized tracer concentration across equal-volume reactor samples, 60 s after dosing.
Normalized concentration at 60 s [–]
Circulation time
Time between consecutive completed circulation loops for tracked parcels.
Circulation time [s]
Accumulated shear exposure
Cumulative mechanical-exposure index; longer or repeated loading produces larger values.
Normalized exposure index [–]
Peak shear rate
Highest local shear rate encountered by each parcel during the observation interval.
Peak shear rate [s⁻¹]
Time above shear threshold
Duration above the 10 s⁻¹ shear-rate threshold, plotted for parcels that experienced at least one exceedance.
Time above 10 s⁻¹ [s]
Relative dosing exposure
Total relative dosing exposure, normalized to a reference of 1.0; not an instantaneous concentration.
Relative dosing exposure [–]
Histogram values are demonstration data, not measurements or exported results from this reactor CFD. The videos and field images below are original project media. Actual mixing-time, concentration and dosing predictions require corresponding tracer or species-transport calculations.
02 / ORIGINAL CFD VISUALIZATIONS
Inside the stirred vessel.
Source animations and numerical field images. Use the timeline to inspect recorded frames or zoom uniformly into local flow structures.
Spatial cell-response fieldOriginal CFD rendering
Video position (recording time)
At 1× the full frame is visible without distortion. The video timestamps are playback times, not physical CFD time.
Working on mixing, shear exposure or dosing uniformity?
Helicon uses CFD and population-based exposure analysis to investigate mixing environments and support engineering decisions.